Farrokh Tabatabai, Ph.D. from LifeLink Foundation, Inc., Tampa, Florida uses ComponentOne Studio WinForms Edition components and has created an application to view information collectively with FlexGrid.
- FlexGrid's extreme flexibility
- Built-in sorting and filtering capabilities
Improving Tissue Typing for Donors
The Transplantation Immunology Laboratory at LifeLink Foundation analyzes and monitors the performance of hundreds of DNA probes that are used to tissue type transplant candidates and potential donors.
The application Farrokh developed with C1FlexGrid accumulates raw data then displays all relevant parameters from each individual assay and sorts by reaction strength. This allows the user to quickly assess whether a probe has a "clean" history of reactivity or exhibits "false positive" and/or "false negative" reactions. If "false" reactions are observed, the filter and sort features of C1 are very helpful in determining which genes (if any) are associated with these "false" reactions. This information is then used to update the interpretive algorithm. This not only makes future interpretation faster, but can actually improve the resolution of the assay.
Dynamic Applications for Dynamic Data
The application is totally dynamic in creating eventual analyses outputs based on results from lab instruments (ad hoc) and long-term back-end databases. This allows LifeLink the freedom of adding and comparing reactions. For interpretation of an individual typing (as opposed to the analysis of the reactivity a single probe over many typings as described above), the application color codes the reactions of all probes in the set, making it easy to identify any potentially missed or extra reactions for that typing.
Before Farrokh developed this application, reactions were evaluated manually on paper. Now they can easily sort and search the reactions. This leads to at least a tenfold increase in productivity as end users can get instant answers to what matters and what does not.
I have been using ComponentOne controls since 2003. The ComponentOne FlexGrid (as well as other C1 controls) gives us extreme flexibility for our dynamic DNA analytical application, which has proven to be the most valuable in our Immunology lab at LifeLink. I use ComponentOne components in several complex .NET projects and find them very useful.